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Hepatocellular cancer TNM staging AJCC UICC 8th edition

Hepatocellular cancer TNM staging AJCC UICC 8th edition
Primary tumor (T)
T category T criteria
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
T1 Solitary tumor ≤2 cm, or >2 cm without vascular invasion
T1a Solitary tumor ≤2 cm
T1b Solitary tumor >2 cm without vascular invasion
T2 Solitary tumor >2 cm with vascular invasion, or multiple tumors, none >5 cm
T3 Multiple tumors, at least one of which is >5 cm
T4 Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein or tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum
Regional lymph nodes (N)
N category N criteria
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis
Distant metastasis (M)
M category M criteria
M0 No distant metastasis
M1 Distant metastasis
Prognostic stage groups
When T is... And N is... And M is... Then the stage group is...
T1a N0 M0 IA
T1b N0 M0 IB
T2 N0 M0 II
T3 N0 M0 IIIA
T4 N0 M0 IIIB
Any T N1 M0 IVA
Any T Any N M1 IVB
TNM: tumor, node, metastasis; AJCC: American Joint Committee on Cancer; UICC: Union for International Cancer Control.
Used with permission of the American College of Surgeons, Chicago, Illinois. The original source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing.
Graphic 110835 Version 9.0

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