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Gallbladder cancer TNM staging AJCC UICC 8th edition

Gallbladder cancer TNM staging AJCC UICC 8th edition
Primary tumor (T)
T category T criteria
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ
T1 Tumor invades the lamina propria or muscular layer
T1a Tumor invades the lamina propria
T1b Tumor invades the muscular layer
T2 Tumor invades the perimuscular connective tissue on the peritoneal side, without involvement of the serosa (visceral peritoneum).
Or tumor invades the perimuscular connective tissue on the hepatic side, with no extension into the liver.
T2a Tumor invades the perimuscular connective tissue on the peritoneal side, without involvement of the serosa (visceral peritoneum)
T2b Tumor invades the perimuscular connective tissue on the hepatic side, with no extension into the liver
T3 Tumor perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts
T4 Tumor invades the main portal vein or hepatic artery or invades two or more extrahepatic organs or structures
Regional lymph nodes (N)
N category N criteria
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastases to one or three regional lymph nodes
N2 Metastases to four or more regional lymph nodes
Distant metastasis (M)
M category M criteria
M0 No distant metastasis
M1 Distant metastasis
Prognostic stage groups
When T is... And N is... And M is... Then the stage group is...
Tis N0 M0 0
T1 N0 M0 I
T2a N0 M0 IIA
T2b N0 M0 IIB
T3 N0 M0 IIIA
T1-3 N1 M0 IIIB
T4 N0-1 M0 IVA
Any T N2 M0 IVB
Any T Any N M1 IVB
TNM: tumor, node, metastasis; AJCC: American Joint Committee on Cancer; UICC: Union for International Cancer Control.
Used with permission of the American College of Surgeons, Chicago, Illinois. The original source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing.
Graphic 110890 Version 9.0

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