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Exocrine pancreatic cancer TNM staging AJCC UICC 8th edition

Exocrine pancreatic cancer TNM staging AJCC UICC 8th edition
Primary tumor (T)
T category T criteria
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ.
This includes high-grade pancreatic intraepithelial neoplasia (PanIn-3), intraductal papillary mucinous neoplasm with high-grade dysplasia, intraductal tubulopapillary neoplasm with high-grade dysplasia, and mucinous cystic neoplasm with high-grade dysplasia.
T1 Tumor ≤2 cm in greatest dimension
T1a Tumor ≤0.5 cm in greatest dimension
T1b Tumor >0.5 and <1 cm in greatest dimension
T1c Tumor 1 to 2 cm in greatest dimension
T2 Tumor >2 and ≤4 cm in greatest dimension
T3 Tumor >4 cm in greatest dimension
T4 Tumor involves the celiac axis, superior mesenteric artery, and/or common hepatic artery, regardless of size
Regional lymph nodes (N)
N category N criteria
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastasis in one to three regional lymph nodes
N2 Metastasis in four or more regional lymph nodes
Distant metastasis (M)
M category M criteria
M0 No distant metastasis
M1 Distant metastasis
Prognostic stage groups
When T is... And N is... And M is... Then the stage group is...
Tis N0 M0 0
T1 N0 M0 IA
T1 N1 M0 IIB
T1 N2 M0 III
T2 N0 M0 IB
T2 N1 M0 IIB
T2 N2 M0 III
T3 N0 M0 IIA
T3 N1 M0 IIB
T3 N2 M0 III
T4 Any N M0 III
Any T Any N M1 IV
TNM: tumor, node, metastasis; AJCC: American Joint Committee on Cancer; UICC: Union for International Cancer Control.
Used with permission of the American College of Surgeons, Chicago, Illinois. The original source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing.
Graphic 111135 Version 10.0

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