Glucocorticoid dosing (upper limit of moderate daily dose range)

Glucocorticoid	Adults	Children	Duration of action (hours)
Prednisone	40 mg	1 mg/kg	12 to 36
Prednisolone	40 mg	1 mg/kg	12 to 36
Methylprednisolone	31 mg	0.8 mg/kg	12 to 36
Hydrocortisone	160 mg	4 mg/kg	8 to 12
Cortisone acetate	200 mg	5 mg/kg	8 to 12
Dexamethasone	6 mg	0.15 mg/kg	26 to 72

The table shows the upper limits of moderate doses for several glucocorticoids. These doses represent thresholds at which significant toxicities begin to appear with extended use in most individuals.

Graphic 111230 Version 2.0

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Glucocorticoid dosing (upper limit of moderate daily dose range)