Rose spots of typhoid fever

Rose spots are small (1 to 5 mm), erythematous, blanchable, nontender papules, which begin early during the acute febrile period of typhoid fever. Crops of lesions (10 to 20) appear at irregular intervals for approximately 10 to 14 days, typically distributed on the abdomen, chest, and back. Rarely, vesicular or hemorrhagic lesions appear. The lesions persist for two to three days.