Version June 2024
| Primary tumor (T) | |||
| T category | T criteria | ||
| TX | Primary tumor cannot be assessed | ||
| T0 | No evidence of primary tumor | ||
| T1* | Invades lamina propria or submucosa and less than or equal to 1 cm in size | ||
| T2* | Invades muscularis propria or greater than 1 cm in size | ||
| T3* | Invades through the muscularis propria into subserosal tissue without penetration of overlying serosa | ||
| T4* | Invades visceral peritoneum (serosal) or other organs or adjacent structures | ||
| * NOTE: For any T, add (m) for multiple tumors [TX(#) or TX(m), where X = 1 to 4 and # = number of primary tumors identified¶]; for multiple tumors with different Ts, use the highest. ¶ Example: If there are two primary tumors, one of which penetrates only the subserosa, we define the primary tumor as either T3(2) or T3(m). | |||
| Regional lymph nodes (N) | |||
| N category | N criteria | ||
| NX | Regional lymph nodes cannot be assessed | ||
| N0 | No regional lymph node metastasis | ||
| N1 | Regional lymph node metastsis | ||
| Distant metastasis (M) | |||
| M category | M criteria | ||
| M0 | No distant metastasis | ||
| M1 | Distant metastasis | ||
| M1a | Metastasis confined to liver | ||
| M1b | Metastases in at least one extrahepatic site (eg, lung, ovary, nonregional lymph node, peritoneum, bone) | ||
| M1c | Both hepatic and extrahepatic metastases | ||
| Prognostic stage groups | |||
| When T is... | And N is... | And M is... | Then the stage group is... |
| TX, T0 | NX, N0, N1 | M1 | IV |
| T1 | N0 | M0 | I |
| T1 | N1 | M0 | III |
| T1 | NX, N0, N1 | M1 | IV |
| T2 | N0 | M0 | II |
| T2 | N1 | M0 | III |
| T2 | NX, N0, N1 | M1 | IV |
| T3 | N0 | M0 | II |
| T3 | N1 | M0 | III |
| T3 | NX, N0, N1 | M1 | IV |
| T4 | N0 | M0 | III |
| T4 | N1 | M0 | III |
| T4 | NX, N0, N1 | M1 | IV |
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