Version June 2024
| Primary tumor (T) | |||
| T category* | T criteria | ||
| TX | Primary tumor cannot be assessed | ||
| T0 | No evidence of primary tumor | ||
| T1 | Tumor invades the lamina propria or submucosa and is ≤2 cm | ||
| T1a | Tumor <1 cm in greatest dimension | ||
| T1b | Tumor 1 to 2 cm in greatest dimension | ||
| T2 | Tumor invades the muscularis propria or is >2 cm with invasion of the lamina propria or submucosa | ||
| T3 | Tumor invades through the muscularis propria into subserosal tissue without penetration of overlying serosa | ||
| T4 | Tumor invades the visceral peritoneum (serosa) or other organs or adjacent structures | ||
| * NOTE: For any T, add (m) for multiple tumors [TX(#) or TX(m), where X = 1 to 4 and # = number of primary tumors identified¶]; for multiple tumors with different T, use the highest. ¶ Example: If there are two primary tumors, only one of which invades through the muscularis propria into the subserosal tissue without penetration of the overlying serosa, we define the primary tumor as either T3(2) or T3(m). | |||
| Regional lymph nodes (N) | |||
| N category | N criteria | ||
| NX | Regional lymph nodes cannot be assessed | ||
| N0 | No regional lymph node metastasis has occurred | ||
| N1 | Regional lymph node metastasis | ||
| Distant metastasis (M) | |||
| M category | M criteria | ||
| M0 | No distant metastasis | ||
| M1 | Distant metastasis | ||
| M1a | Metastasis confined to liver | ||
| M1b | Metastases in at least one extrahepatic site (eg, lung, ovary, nonregional lymph node, peritoneum, bone) | ||
| M1c | Both hepatic and extrahepatic metastases | ||
| Prognostic stage groups | |||
| When T is... | And N is... | And M is... | Then the stage group is... |
| TX, T0 | Any N | M1 | IV |
| T1 | N0 | M0 | I |
| T1 | N1 | M0 | IIIB |
| T1 | Any N | M1 | IV |
| T2 | N0 | M0 | IIA |
| T2 | N1 | M0 | IIIB |
| T2 | Any N | M1 | IV |
| T3 | N0 | M0 | IIB |
| T3 | N1 | M0 | IIIB |
| T3 | Any N | M1 | IV |
| T4 | N0 | M0 | IIIA |
| T4 | N1 | M0 | IIIB |
| T4 | Any N | M1 | IV |
| NOTE: For multiple synchronous tumors, the highest T category should be used and the multiplicity or the number of tumors should be indicated in parenthesis, eg, T3(2) or T3(m). | |||
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