Histopathologic features of the affected skin in H syndrome at scanning magnification. (A) Widespread fibrosis, moderate in the dermis and marked in the subcutis, noticeably widening the interlobular septae and (B) wiping out subcutaneous fat. H&E stain, original magnification x25.
From: Doviner V, Maly A, Ne'eman Z, et al. H syndrome: recently defined genodermatosis with distinct histologic features. A morphological, histochemical, immunohistochemical, and ultrastructural study of 10 cases. Am J Dermatopathol 2010; 32(2):118-28. DOI:
10.1097/DAD.0b013e3181b28572. Copyright © 2010 International Society of Dermatopathology. Reproduced with permission from Lippincott Williams & Wilkins. Unauthorized reproduction of this material is prohibited.