Society guideline links: Well-differentiated gastroenteropancreatic neuroendocrine tumors

Introduction — This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.

The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.

Links to related guidelines are provided separately. (See "Society guideline links: Pancreatic cancer".)

International

●VHL Alliance (VHLA): Consensus guidelines for management recommendations for pancreatic manifestations of von Hippel-Lindau disease (2022)

●European-African Hepato-Pancreatico-Biliary Association (E-AHPBA), Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland (AUGIS), European Neuroendocrine Tumour Society (ENETS), European Society of Surgical Oncology (ESSO), Great Britain and Ireland Hepato Pancreatico Biliary Association (GBIHPBA), International Hepato-Pancreato-Biliary Association (IHPBA), International Liver Transplantation Society (ILTS), United Kingdom and Ireland Neuroendocrine Tumour Society (UKINET), NET Patient Foundation, and Carcinoid Foundation: Recommendations for management of patients with neuroendocrine liver metastases (2014)

●International Atomic Energy (IAEA), European Association of Nuclear Medicine (EANM), and Society of Nuclear Medicine and Molecular Imaging (SNMMI): Practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours (2013)

Canada

●North American Neuroendocrine Tumor Society (NANETS): Consensus guidelines

•NANETS: Consensus guidelines for surveillance and medical management of pancreatic neuroendocrine tumors (2020)

•NANETS: Consensus paper on the surgical management of pancreatic neuroendocrine tumors (2020)

•NANETS: Consensus guidelines for surveillance and medical management of midgut neuroendocrine tumors (2017)

•NANETS: Consensus guidelines for the surgical management of small bowel neuroendocrine tumors (2017)

•NANETS: Consensus guidelines for the management and treatment of neuroendocrine tumors (2013)

●Commonwealth Neuroendocrine Tumour Research Collaboration (CommNETs) and NANETS: Guidelines for the diagnosis and management of patients with lung neuroendocrine tumors – An international collaborative endorsement and update of the 2015 European Neuroendocrine Tumor Society (ENETS) expert consensus guidelines (2020)

●NANETS/Society of Nuclear Medicine and Molecular Imaging (SNMMI): Consensus statement on patient selection and appropriate use of 177Lu-DOTATATE peptide receptor radionuclide therapy (2020)

●Cancer Care Ontario (CCO): Gallium-68 PET imaging in neuroendocrine tumours (2018)

●NANETS and SNMMI: Appropriate use criteria for somatostatin receptor PET imaging in neuroendocrine tumors (2017)

●CCO: Systemic therapy of incurable gastroenteropancreatic neuroendocrine tumours (2016)

●Canadian National Expert Group: Consensus recommendations for the diagnosis and management of pancreatic neuroendocrine tumors – Guidelines (2014)

●CCO: Expert panel report – Radionuclide therapy for patients with neuroendocrine tumors (NETs) in Ontario (2011)

●CCO: Radionuclide therapy for neuroendocrine malignancies (2011)

●Canadian National Expert Group: Consensus recommendations for the diagnosis and management of well-differentiated gastroenterohepatic neuroendocrine tumors − A revised statement (2010)

United States

●American Society of Clinical Oncology (ASCO): Guideline on systemic therapy for tumor control in metastatic well-differentiated gastroenteropancreatic neuroendocrine tumors (2023)

●North American Neuroendocrine Tumor Society (NANETS): Consensus guidelines

•NANETS: Consensus guidelines for surveillance and medical management of pancreatic neuroendocrine tumors (2020)

•NANETS: Consensus paper on the surgical management of pancreatic neuroendocrine tumors (2020)

•NANETS: Consensus guidelines for surveillance and medical management of midgut neuroendocrine tumors (2017)

•NANETS: Consensus guidelines for the surgical management of small bowel neuroendocrine tumors (2017)

•NANETS: Consensus guidelines for the management and treatment of neuroendocrine tumors (2013)

●Commonwealth Neuroendocrine Tumour Research Collaboration (CommNETs) and NANETS: Guidelines for the diagnosis and management of patients with lung neuroendocrine tumors – An international collaborative endorsement and update of the 2015 European Neuroendocrine Tumor Society (ENETS) expert consensus guidelines (2020)

●NANETS/Society of Nuclear Medicine and Molecular Imaging (SNMMI): Consensus statement on patient selection and appropriate use of 177Lu-DOTATATE peptide receptor radionuclide therapy (2020)

●NANETS and SNMMI: Appropriate use criteria for somatostatin receptor PET imaging in neuroendocrine tumors (2017)

Europe

●European Society for Medical Oncology (ESMO): Clinical practice guidelines for diagnosis, treatment and follow-up of gastroenteropancreatic neuroendocrine neoplasms (2020)

●European Neuroendocrine Tumour Society (ENETS): Consensus guidelines for the standards of care in neuroendocrine neoplasms – Peptide receptor radionuclide therapy with radiolabelled somatostatin analogues (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine neoplasms – Systemic therapy: Biotherapy and novel targeted agents (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine neoplasms – Systemic therapy: Chemotherapy (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine tumors – Biochemical markers (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine tumors – Pathology: Diagnosis and prognostic stratification (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine tumors – Pre- and perioperative therapy in patients with neuroendocrine tumors (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine tumors – Radiological, nuclear medicine, and hybrid imaging (2017)

●ENETS: Consensus guidelines for the standards of care in neuroendocrine tumours – Surgery for small intestinal and pancreatic neuroendocrine tumours (2017)

●ENETS: Consensus recommendations for the standards of care in neuroendocrine neoplasms – Follow-up and documentation (2017)

●ENETS: Consensus guidelines for colorectal neuroendocrine neoplasms, update (2016)

●ENETS: Consensus guidelines for gastroduodenal neuroendocrine neoplasms, update (2016)

●ENETS: Consensus guidelines for high-grade gastroenteropancreatic neuroendocrine tumors and neuroendocrine carcinomas (2016)

●ENETS: Consensus guidelines for neuroendocrine neoplasms of the appendix (excluding goblet cell carcinomas) (2016)

●ENETS: Consensus guidelines for neuroendocrine neoplasms of the jejunum and ileum, update (2016)

●ENETS: Consensus guidelines for the management of distant metastatic disease of intestinal, pancreatic, bronchial neuroendocrine neoplasms (NEN), and NEN of unknown primary site, update (2016)

●ENETS: Consensus guidelines for the management of patients with digestive neuroendocrine tumors – Well-differentiated jejunal-ileal tumor/carcinoma (2016)

●ENETS: Consensus guidelines for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine tumors, update (2016)

United Kingdom

●Royal College of Pathologists (RCPath): Standards and datasets for reporting cancers – Dataset for histopathological reporting of neuroendocrine neoplasms of the gastroenteropancreatic tract (2019)

●UK and Ireland Neuroendocrine Tumour Society (UKINETS): Guidance for the use of zoledronic acid/denosumab in patients with bone metastases from neuroendocrine tumours (NETs) (2019)

●Scottish Neuroendocrine Tumour Group (SCONET): Consensus guidelines for the management of patients with neuroendocrine tumours (2015, updated 2018)

●UKINETS: Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs) (2012)

India

●Indian Council of Medical Research (ICMR): Consensus document for management of neuroendocrine tumours (GEP-NETs) (2019)

Australia–New Zealand

●Clinical Oncology Society of Australia (COSA): NETs guidelines (revised 2014)

●Government of South Australia (SA Health): South Australian gastroenteropancreatic neuroendocrine tumours pathway (2013)

Japan

●[In Japanese] Japan Neuroendocrine Tumor Society (JNETS): Clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN), 2nd edition (2019)