Version July 2025
AKI: acute kidney injury; SCr: serum creatinine.
* This algorithm reflects the diagnostic evaluation of the author for the UpToDate topic on the evaluation, management, and prognosis of neonatal AKI.
¶ Details of the underlying etiologies can be found in the UpToDate topic on etiology of neonatal AKI.
Δ Refer to UpToDate topics on kidney cystic disease and renal hypodysplasia.
◊ The fluid challenge consists of the intravenous administration of 10 to 20 mL/kg of isotonic saline given over 1 to 2 hours.