(A) Left lower eyelid. Loss of lashes, conjunctival injection, and meibomian capping can be seen. The disruption of the mucocutaneous junction is seen across the eyelid margin. Middle lamellar shortening secondary to tarsal "melt" can be slightly appreciated from the figure.
(B) Periodic acid-Schiff, magnification x100. Shows cells in the epidermis with dark cytoplasm that may represent "corps ronds" cells seen in Darier disease (arrow).
From: Czyz C, Sharma P, Grossniklaus HE, et al. Clinical and pathologic eyelid alterations in a patient with Darier disease. Ophthal Plast Reconstr Surg 2011; 27:e170. DOI:
10.1097/IOP.0b013e31820cd645. Copyright © 2011 American Society of Ophthalmic Plastic and Reconstructive Surgery. Reproduced with permission from Lippincott Williams & Wilkins. Unauthorized reproduction of this material is prohibited.