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Cysts, blebs, bullae, cavities, honeycombing, pneumatoceles: Definitions and features[1]

Cysts, blebs, bullae, cavities, honeycombing, pneumatoceles: Definitions and features[1]
  Features Examples
Bleb Previously, "bleb" referred to a rounded, subpleural lucency, <1 cm diameter. Now considered to be a type of bulla, and use of the term is discouraged.  
Bulla Rounded, focal, thin-walled (<1 mm); usually several centimeters in diameter, can fill hemithorax, can be seen in association with emphysema. Emphysema.
Bronchiectasis Dilated, thick-walled bronchi can look cystic, but are in communication with airway; may be clustered. Cystic fibrosis, primary ciliary dysfunction, common variable immunodeficiency, postinfectious.
Cavity Thick walled (>4 mm) may be partially filled with fluid, debris, mycetoma. Can be within a mass, nodule, or area of consolidation. Necrotizing bacterial pneumonia, mycobacterial or fungal infection, neoplasm (eg, bronchogenic carcinoma if single; metastatic cancer if multiple), granulomatosis with polyangiitis (GPA) and other vasculitides.
Cyst Round or irregular, variable size, thin-walled (<2 mm thick), may be associated with nodules. Birt-Hogg-Dubé syndrome, lymphangioleiomyomatosis, lymphocytic interstitial pneumonia, pulmonary Langerhans cell histiocytosis.
Emphysema Rounded or polygonal lucencies without walls; variable size. Paraseptal emphysema is bounded by pleura and interlobular septa; centrilobular emphysema has an upper lobe predilection. Alpha-1 antitrypsin deficiency, lung injury due to cigarette smoking or indoor cooking fires.
Honeycombing Clusters of round, 3 to 10 mm diameter lucencies, wall-thickness 1 to 3 mm; may be multitiered, typically in a subpleural location, associated with traction bronchiectasis and septal thickening. Asbestosis, idiopathic pulmonary fibrosis (IPF), usual interstitial pneumonia in systemic rheumatic disease, chronic hypersensitivity pneumonitis.
Pneumatocele Often postinfectious, may be solitary or multiple, typically transient. Postinfectious (eg, Staphylococcus aureus pneumonia, Pneumocystis jirovecii pneumonia, coccidioidomycosis), post-traumatic, hydrocarbon inhalation.
Reference:
  1. Hansell DM, Bankier AA, MacMahon H, et al. Fleischner Society: glossary of terms for thoracic imaging. Radiology 2008; 246:697.
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