Version June 2024
| Generic name | Nitrous oxide | Halothane | Isoflurane | Sevoflurane | Desflurane |
| Brand name | N/A | Fluothane | Forane | Ultane | Suprane |
| Chemical formula | N2O | C2HBrClF3 | C3H2ClF5O | C4H3F7O | C3H2F6O |
| Odor | Slightly sweet | Sweet | Sweet | Sweet | Sweet |
| Color | Colorless | Colorless | Colorless | Colorless | Colorless |
| Pungency | None | Moderate | High | Low | Very high |
| Solubility:blood:gas partition coefficient | Very low: 0.46 | Very high: 2.40 | Moderately high: 1.40 | Low: 0.65 | Very low: 0.45 |
| Redistribution:brain:blood partition coefficient | 1.1 | 1.9 | 1.6 | 1.7 | 1.3 |
| Potency:oil:gas partition coefficient | Very low: 1.4 | Very high: 224.0 | High: 97.0 | Moderately high: 42.0 | Low: 18.7 |
| Minimum alveolar concentration (MAC) = ED50 for response to surgery | 105.0% | 0.8% | 1.2% | 2.0% | 6.0% |
| MAC-awake/MAC-aware = ED50 for response to voice/touch | 68.0% | 0.4% | 0.5% | 0.6% | 2.5% |
| Blood pressure effect | Negligible | Dose-dependent hypotension | Dose-dependent hypotension | Dose-dependent hypotension | Dose-dependent hypotension |
| Vascular effect | Negligible | Negligible | Vasodilation | Vasodilation | Initial vasoconstriction, later vasodilation |
| Inotropic effect | Negligible | Negative | Slightly negative | Slightly negative | Initial positive, later negative |
| Chronotropic effect | Negligible | Bradycardia | Tachycardia | Tachycardia >1 MAC | Tachycardia |
| How supplied | Pressurized bottled gas | Bottled liquid | Bottled liquid | Bottled liquid | Bottled liquid |
| How delivered | Flowmeter | Vaporizer | Vaporizer | Vaporizer | Electric heated vaporizer |
| Fire risk | Supports combustion | Non-flammable | Non-flammable | Non-flammable | Non-flammable |
| Notes | Nausea/emesis | Nausea/emesis; bradycardia/asystole; inhalational induction; no longer used in US | Nausea/emesis; potentially significant tachycardia | Nausea/emesis; inhalational induction | Nausea/emesis; airway irritation; initial sympathomimetic |
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