Probable DLB |
|
Possible DLB |
|
DLB is less likely |
|
Essential features | DementiaΔ |
Core clinical features (the first three typically occur early and may persist throughout the course) |
|
Supportive clinical features |
|
Indicative biomarkers |
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Supportive biomarkers |
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DLB: dementia with Lewy bodies; REM: rapid eye movement; SPECT: single-photon emission computed tomography; PET: positron emission tomography; MIBG: metaiodobenzylguanidine; CT: computed tomography; MRI: magnetic resonance imaging; FDG: fluorodeoxyglucose; EEG: electroencephalography.
* These do not exclude a DLB diagnosis and may serve to indicate mixed or multiple pathologies contributing to the clinical presentation.
¶ DLB should be diagnosed when dementia occurs before or concurrently with parkinsonism. The term "Parkinson disease dementia" (PDD) should be used to describe dementia that occurs in the context of well-established Parkinson disease.
Δ Dementia is defined as a progressive cognitive decline of sufficient magnitude to interfere with normal social or occupational functions, or with usual daily activities. Prominent or persistent memory impairment may not necessarily occur in the early stages but is usually evident with progression. Deficits on tests of attention, executive function, and visuoperceptual ability may be especially prominent and occur early.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟