Version May 2024
| Antidepressant* | Dose (mg/day) |
| Agomelatine (United States: Not available) | 53 |
| Amitriptyline | 122 |
| Bupropion | 349 |
| Clomipramine | 116 |
| Desipramine | 196 |
| Dothiepin (United States: Not available) | 155 |
| Doxepin | 140 |
| Escitalopram | 18 |
| Fluvoxamine | 143 |
| Imipramine | 137 |
| Lofepramine (United States: Not available) | 250 |
| Maprotiline (United States: Not available) | 118 |
| Mianserin (United States: Not available) | 101 |
| Mirtazapine | 51 |
| Moclobemide¶ (United States: Not available) | 575 |
| Nefazodone | 535 |
| Nortriptyline | 101 |
| Paroxetine | 34 |
| Reboxetine (United States: Not available) | 12 |
| Sertraline | 99 |
| Trazodone | 401 |
| Venlafaxine | 149 |
The doses listed here are not recommended for initiating therapy. Rather, the doses provide a starting point for the purpose of comparing and switching different antidepressants during maintenance therapy for unipolar depression. Dose equivalences are only one of several factors to consider for targeting a dose range when switching antidepressants; refer to UpToDate topic text.
The estimated dose equivalence will generally require rounding to the nearest available product strength(s), which can be found in the Lexicomp drug-specific monographs included within UpToDate.MAOI: monoamine oxidase inhibitor.
* Dose equivalence for some antidepressants, such as citalopram and duloxetine, were not available. Citalopram is considered approximately one-half as potent as escitalopram; based on escitalopram equivalence data, citalopram 36 mg appears to be equivalent to fluoxetine 40 mg.
¶ Moclobemide is a reversible MAOI; switching to or from an MAOI requires specific precautionary measures. Refer to UpToDate text.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
