Differential muscle sensitivity to rocuronium

Approximate time course of twitch height reduction and recovery at different muscles after administration of rocuronium 0.6 mg/kg IV.

Larynx: laryngeal adductors (vocal cords); CS: corrugator supercilii muscle (eyebrow); Abd: abdominal muscles; OO: orbicularis oculi muscle (eyelid); GH: geniohyoid muscle (upper airway); AP: adductor pollicis muscle (thumb); IV: intravenous.

Reproduced with permission from: Brull SJ. Neuromuscular blocking agents. In: Clinical Anesthesia, 8th ed, Barash PG, Cullen BF, Stoelting RK, et al (Eds), Wolters Kluwer, Philadelphia 2017. Copyright © 2017 Wolters Kluwer Health.

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Differential muscle sensitivity to rocuronium