Cutaneous plaques in progestogen hypersensitivity

Patient was seen with round, 1- to 2-cm dark, erythematous, scaly plaques on her face, neck, abdomen, chest, pelvis, and lower back, which slowly faded to dark purple color but did not clear entirely before the start of her next cycle, when a new crop would appear at the same anatomic location. The previous month, she also had lip and eyelid swelling and an oral mucosa lesion. Skin lesions in two consecutive months are shown.