Rapid oral progesterone desensitization*

Protocol step	Oral capsules dose (mcg)	Number of capsules	Total dose	Time interval (minutes)
1	1	1	1	30
2	1	2	2	30
3	1	5	5	30
4	10	1	10	30
5	10	2	20	30
6	10	5	50	30
7	100	1	100	30

Note that this protocol has been performed in a very small number of patients by experienced allergy specialists. The efficacy in larger numbers of patients awaits further study. UpToDate suggests that allergy specialists supervise such protocols whenever possible.

* With use of capsules made at a compounding pharmacy.

Original figure modified for this publication. Reproduced from: Prieto-Garcia A, Sloane DE, Gargiulo AR, et al. Autoimmune progesterone dermatitis: Clinical presentation and management with progesterone desensitization for successful in vitro fertilization. Fertil Steril 2011; 95:1121.e9. Table used with the permission of Elsevier Inc. All rights reserved.

Graphic 116121 Version 3.0

خرید پکیج

Rapid oral progesterone desensitization*