COL: colonoscopy; CTC: computed tomography colonography; FIT: fecal immunochemical test; FIT-DNA: multitargeted stool deoxyribonucleic acid test; gFOBT: guaiac-based fecal occult blood test; SIG: sigmoidoscopy.
* Assumes screening from ages 50 to 75 years, including 100% adherence, complete follow-up without delay, and appropriate surveillance. Ranges reflect results from 3 models.