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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Summary of secondary prevention ICD trials[1]

Summary of secondary prevention ICD trials[1]
Study AVID[2] CASH[3] CIDS[4] NCDR Cohort[5]
Years 1993 to 1997 1987 to 1998 1990 to 1997 2006 to 2009
Patients 1016 191 659 46,685
Mean age (years) 65±11 58±11 63±9 66±14
Male (%) 78 79 85 73
Follow-up (months) 18±12 57±34 36 None
CAD (%) 81 73 83 64
Nonischemic (%) 15 12 10 23
LVEF 32±13 46±19 34±14 36±15
Presenting arrhythmia (%)
VF 45 100 45 51
VT with LOC 21 0 16 NR
VT without LOC 34 0 24 27
Syncope 0 0 15 22
BB (%) 42 0 33 84
ACE-I/ARB (%) 69 45 NR 72
One-year mortality (%): Control/ICD 17.7/10.7 15.2/8.1 11.2/9.5 NA/10.4
Two-year mortality (%): Control/ICD 25.3/18.4 27.2/17.2 21.0/14.8 NA/16.4
ICD: implantable cardioverter-defibrillator; CAD: coronary artery disease; LVEF: left ventricular ejection fraction; VF: ventricular fibrillation; VT: ventricular tachycardia; LOC: loss of consciousness; BB: beta blocker; ACE-I: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; NR: not recorded; NA: not applicable.
References:
  1. Borne R, Katz D, Betz J, et al. Implantable Cardioverter-Defibrillators for Secondary Prevention of Sudden Cardiac Death: A Review. J Am Heart Assoc 2017; 6:e005515.
  2. Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Engl J Med 1997; 337:1576.
  3. Kuck KH, Cappato R, Siebels J, Rüppel R. Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest: the Cardiac Arrest Study Hamburg (CASH). Circulation 2000; 102:748.
  4. Connolly SJ, Gent M, Roberts RS, et al. Canadian implantable defibrillator study (CIDS): a randomized trial of the implantable cardioverter defibrillator against amiodarone. Circulation 2000; 101:1297.
  5. Katz DF, Peterson P, Borne RT, et al. Survival after secondary prevention ICD placement: an analysis from the NCDR ICD Registry. JACC Clin Electrophysiol 2017; 3:20.
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