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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Crude incidence rates at one-year of follow-up in the Heart Failure Study Population, stratified according to prior diagnosis of atrial fibrillation*

Crude incidence rates at one-year of follow-up in the Heart Failure Study Population, stratified according to prior diagnosis of atrial fibrillation*
End points Overall Number of additional risk factors on CHA2DS2-VASc score
1 (HF only) 2 3 4 5 ≥6
Patients without atrial fibrillation
Patients, number (%) 33,592 2366 (7.0) 4503 (13.4) 7462 (22.2) 9183 (27.3) 5958 (17.7) 4120 (12.3)
Ischemic stroke
Events, number 977 29 62 141 258 212 275
Person-years, number 9,448,812 711,473 1,393,807 2,180,746 2,529,593 1,599,137 707,004
Incidence rate, % (95% CI) 1.0 (1.0-1.1) 0.4 (0.3-0.6) 0.4 (0.3-0.6) 0.6 (0.5-0.8) 1.0 (0.9-1.2) 1.3 (1.2-1.5) 2.6 (2.4-3.0)
Thromboembolism
Events, number 3187 110 276 548 853 683 717
Person-years, number 9,040,950 696,366 1,348,456 2,104,494 2,421,856 1,518,482 652,067
Incidence rate, % (95% CI) 3.5 (3.4-3.6) 1.6 (1.3-1.9) 2.0 (1.8-2.3) 2.6 (2.4-2.8) 3.5 (3.3-3.8) 4.5 (4.2-4.8) 7.5 (7.0-8.1)
Death
Events, number 6956 149 332 1256 2239 1596 1384
Person-years, number 9,596,399 715,795 1,404,213 2,201,781 2,566,123 1,632,315 731,311
Incidence rate, % (95% CI) 7.2 (7.1-7.4) 2.1 (1.8-2.4) 2.4 (2.1-2.6) 5.7 (5.4-6.0) 8.7 (8.4-9.1) 9.8 (9.3-10.3) 12.9 (12.2-13.6)
Patients with atrial fibrillation
Patients, number (%) 9395 606 (6.5) 931 (9.9) 1752 (18.7) 2571 (27.4) 137 (20.6) 1598 (17.0)
Ischemic stroke
Events, number 318 8 11 32 82 80 105
Person-years, number 1,592,497 55,019 110,265 294,757 477,528 365,633 180,083
Incidence rate, % (95% CI) 2.0 (1.8-2.2) 1.5 (0.7-2.9) 1.0 (0.6-1.8) 1.1 (0.8-1.5) 1.7 (1.4-2.1) 2.2 (1.8-2.7) 3.6 (3.0-4.4)
Thromboembolism
Events, number 651 18 31 85 158 169 190
Person-years, number 1,551,095 54,425 107,277 287,648 468,813 357,479 172,156
Incidence rate, % (95% CI) 4.2 (3.9-4.5) 3.3 (2.1-5.2) 2.9 (2.0-4.1) 3.0 (2.4-3.7) 3.4 (2.9-3.9) 4.7 (4.1-5.5) 6.9 (6.0-8.0)
Death
Events, number 2153 11 47 282 677 561 575
Person-years, number 1,630,977 55,347 111,192 297,304 489,042 373,574 186,490
Incidence rate, % (95% CI) 13.2 (12.7-13.8) 2.0 (1.1-3.6) 4.2 (3.2-5.6) 9.5 (8.4-10.7) 13.8 (12.8-14.9) 15.0 (13.8-16.3) 18.9 (17.4-20.5)
HF: heart failure.
* CHA2DS2-VASc score is calculated as congestive heart failure (1 point), hypertension (1 point), age 75 years or older (2 points), diabetes (1 point), stroke/transient ischemic attack/thromboembolism (2 points), vascular disease (prior myocardial infarction, peripheral artery disease, or aortic plaque; 1 point), age 65 to 75 years (1 point), female sex (1 point). All study patients had heart failure at baseline.
¶ Composite end point of ischemic stroke, transient ischemic attack, systemic embolism, pulmonary embolism, or acute myocardial infarction.
Reproduced with permission from: Melgaard L, Gorst-Rasmussen A, Lane DA, et al. Assessment of the CHA2DS2-VASc Score in Predicting Ischemic Stroke, Thromboembolism, and Death in Patients With Heart Failure With and Without Atrial Fibrillation. JAMA 2015; 314:1030. Copyright © 2015 American Medical Association. All rights reserved.
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