Preoperative MRI and positive margin rates

Study	Intervention		Positive margin rate		Re-excision rate
Study	Arm	n	Percent	p value	Percent	p value
COMICE^[1]	MRI	816	13*	NS	16	0.77
COMICE^[1]	No MRI	807	15*	NS	19	0.77
MONET^[2]	MRI	74	NS	NS	45^¶	0.069
	No MRI	75	NS		28^¶
	SOC	116	34		21

MRI: magnetic resonance imaging; NS: not specified; SOC: standard of care.
* Positive margins stated are for invasive disease only.
¶ Re-excision rates stated are for re-excision (breast-conserving surgery) and conversion to mastectomy after initial surgery.

References:

Turnbull L, Brown S, Harvey I, et al. Comparative effectiveness of MRI in breast cancer (COMICE) trial: A randomised controlled trial. Lancet 2010; 375:563.
Peters NH, van Esser S, van den Bosch MA, et al. Preoperative MRI and surgical management in patients with nonpalpable breast cancer: The MONET - randomised controlled trial. Eur J Cancer 2011; 47:879.

Graphic 117264 Version 1.0

خرید پکیج

Preoperative MRI and positive margin rates