Society guideline links: Thrombotic microangiopathies (TTP, HUS, and related disorders)

Introduction — This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.

The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.

Links to related guidelines are provided separately. (See "Society guideline links: Hemolytic uremic syndrome in children".)

International

●International Society on Thrombosis and Haemostasis (ISTH): Good practice statements (GPS) for the clinical care of patients with thrombotic thrombocytopenic purpura (2020)

●ISTH: Guidelines for the diagnosis of thrombotic thrombocytopenic purpura (2020)

●ISTH: Guidelines for treatment of thrombotic thrombocytopenic purpura (2020)

●International Council for Standardization in Haematology (ICSH): Recommendations for identification, diagnostic value, and quantitation of schistocytes (2012)

United States

●Centers for Disease Control and Prevention (CDC): Recommendations for diagnosis of Shiga toxin-producing Escherichia coli infections by clinical laboratories (2009)

Europe

●European Paediatric Study Group for HUS: Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome (2009)

United Kingdom

●British Society for Haematology (BSH): Guideline for diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies (2023)

●British Committee for Standards in Haematology (BCSH): Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies (2012)

●Renal Association (RA), BCSH, and British Transplantation Society (BTS): Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom (2009)

India

●Indian Society of Pediatric Nephrology (ISPN): Hemolytic uremic syndrome in a developing country – Consensus guidelines (2019)

Australia–New Zealand

●New South Wales Ministry of Health (NSW Health): Haemolytic uraemic syndrome (HUS) and shigatoxigenic E. coli infections (STEC) control guideline (2012, revised 2016)

Japan

●[In English] Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) in Japan (2017)

●[In Japanese] Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) in Japan (2017)

●[In English] Japanese Society of Nephrology (JSN) and Japan Pediatric Society (JPS): Clinical guides for atypical hemolytic uremic syndrome in Japan (2016)

●[In Japanese] JSN and JPS: Clinical guides for atypical hemolytic uremic syndrome in Japan (2016)

●[In English] Japanese Society for Pediatric Nephrology (JSPN): Guidelines for the management and investigation of hemolytic uremic syndrome (2014)

●[In Japanese] JSPN: Guidelines for the management and investigation of hemolytic uremic syndrome (2014)

●[In English] JSN and JPS: Diagnostic criteria for atypical hemolytic uremic syndrome (2014)

●[In Japanese] JSN and JPS: Diagnostic criteria for atypical hemolytic uremic syndrome (2013)