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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Studies reporting five-year survival in early stage HCC after RFA as the first-line nonsurgical therapy, stratified by Child-Turcotte-Pugh stage

Studies reporting five-year survival in early stage HCC after RFA as the first-line nonsurgical therapy, stratified by Child-Turcotte-Pugh stage
Study Number of patients Overall survival rate (%)
At one year At three years At five years
Lencioni et al (2005)1

Child-Pugh A: 144

Child-Pugh B: 43

Child-Pugh A: 100

Child-Pugh B: 89

Child-Pugh A: 76

Child-Pugh B: 46

Child-Pugh A: 51

Child-Pugh B: 31
Tateishi et al (2005)2

Child-Pugh A: 221

Child-Pugh B to C*: 98

Child-Pugh A: 96

Child-Pugh B to C: 90

Child-Pugh A: 83

Child-Pugh B to C: 65

Child-Pugh A: 63

Child-Pugh B to C: 31
Choi et al (2007)3

Child-Pugh A: 359

Child-Pugh B: 160

Child-Pugh A: NR

Child-Pugh B: NR

Child-Pugh A: 78

Child-Pugh B: 49

Child-Pugh A: 64

Child-Pugh B: 38
N'Kontchou et al (2009)4

Resectable: 67

Unresectable: 168

Resectable: NR

Unresectable: NR

Resectable: 82

Unresectable: 49

Resectable: 76

Unresectable: 27
HCC: hepatocellular carcinoma; RFA: radiofrequency ablation; NR: not reported; BCLC: Barcelona Clinic for Liver Cancer.
* Only 4 of 98 patients had Child-Pugh C cirrhosis.
¶ Based upon BCLC criteria for resection: single tumor, normal bilirubin level (<1.5 mg/dL), and absence of significant portal hypertension.
References:
  1. Lencioni R, Cioni D, Crocetti L, et al. Early-stage hepatocellular carcinoma in cirrhosis: long-term results of percutaneous image-guided radiofrequency ablation. Radiology 2005; 234:961.
  2. Tateishi R, Shiina S, Teratani T, et al. Percutaneous radiofrequency ablation for hepatocellular carcinoma. An analysis of 1000 cases. Cancer 2005; 103:1201.
  3. Choi D, Lim HK, Rhim H, et al. Percutaneous radiofrequency ablation for early-stage hepatocellular carcinoma as a first-line treatment: long-term results and prognostic factors in a large single-institution series. Eur Radiol 2007; 17:684.
  4. N'Kontchou G, Mahamoudi A, Aout M, et al. Radiofrequency ablation of hepatocellular carcinoma: long-term results and prognostic factors in 235 Western patients with cirrhosis. Hepatology 2009; 50:1475.
Reprinted by permission from: Macmillan Publishers Ltd: Nature Reviews Clinical Oncology. Breen DJ, Lencioni R. Image-guided ablation of primary liver and renal tumours. Nat Rev Clin Oncol 2015; 12:175. Copyright © 2015. http://www.nature.com/nrclinonc/.
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