Tenofovir disoproxil fumarate: Patient drug information
(For additional information see "Tenofovir disoproxil fumarate: Drug information" and see "Tenofovir disoproxil fumarate: Pediatric drug information")
You must carefully read the "Consumer Information Use and Disclaimer" below in order to understand and correctly use this information.
Brand Names: Canada
- AG-Tenofovir;
- APO-Tenofovir;
- Auro-Tenofovir;
- JAMP-Tenofovir;
- MINT-Tenofovir;
- MYLAN-Tenofovir Disoproxil;
- NAT-Tenofovir;
- PMS-Tenofovir;
- RIVA-Tenofovir;
- TEVA-Tenofovir;
- Viread
Warning
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Hepatitis B has gotten worse when this drug was stopped in some people with hepatitis B. Close follow-up for a few months is needed when therapy is stopped in people who have hepatitis B. Do not stop taking this drug without calling your doctor.
What is this drug used for?
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It is used to treat HIV infection.
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It is used to treat hepatitis B infection.
What do I need to tell my doctor BEFORE I take this drug?
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If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
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If you are taking another drug that has the same drug in it.
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If you are taking adefovir.
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If you are taking any drugs that can raise the chance of kidney problems. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
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If you are breast-feeding or plan to breast-feed.
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This is not a list of all drugs or health problems that interact with this drug.
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Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take this drug?
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For all uses of this drug:
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Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
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Bone problems like bone pain, soft bones, and thin bones have happened. This may lead to broken bones. You may need to have a bone test.
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Take calcium and vitamin D as you were told by your doctor.
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Have your blood work and other lab tests checked as you have been told by your doctor.
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This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors.
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Kidney problems like kidney failure have happened with this drug. Tell your doctor if you have ever had kidney problems.
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Rarely, this drug may cause a swollen liver and a buildup of acid in the blood. Sometimes, this may be deadly. The risk may be higher in females, in overweight people, and in people who have taken drugs like this one for a long time.
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If giving this drug to your child and your child's weight changes, talk with the doctor. The dose of this drug may need to be changed.
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Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
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Treating HIV infection:
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This drug is not a cure for HIV. Stay under the care of your doctor.
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Hepatitis B testing needs to be done as you were told by the doctor. Talk with the doctor.
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Hepatitis B infection:
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This drug is not a cure for hepatitis infection. Stay under the care of your doctor.
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You will need to have an HIV test as you were told by your doctor. Talk with your doctor.
What are some side effects that I need to call my doctor about right away?
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WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
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For all uses of this drug:
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Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
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Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
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Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
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Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.
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Depression.
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Bone pain.
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Muscle pain or weakness.
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Pain in arms or legs.
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A burning, numbness, or tingling feeling that is not normal.
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Treating HIV infection:
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Changes in your immune system can happen when you start taking drugs to treat HIV. If you have an infection that you did not know you had, it may show up when you take this drug. Tell your doctor right away if you have any new signs after you start this drug, even after taking it for several months. This includes signs of infection like fever, sore throat, weakness, cough, or shortness of breath.
What are some other side effects of this drug?
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All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
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Headache.
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Feeling dizzy, tired, or weak.
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Upset stomach or throwing up.
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Stomach pain or diarrhea.
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Trouble sleeping.
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These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
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You may report side effects to your national health agency.
How is this drug best taken?
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Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
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All products:
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Take this drug at the same time of day.
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It is important that you do not miss or skip a dose of this drug during treatment.
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Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
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Tablets:
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Take with or without food.
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Powder:
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Wash your hands before and after use.
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Use only the scoop that comes with the powder to measure powder.
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Mix powder with 2 to 4 ounces (60 to 120 mL) of a soft food like applesauce, baby food, or yogurt. Swallow right away without chewing. Chewing the food may make it taste very bad.
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Do not mix with any liquid.
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Wash and dry the scoop after each use. Do not store it in the bottle.
What do I do if I miss a dose?
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Take a missed dose as soon as you think about it.
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If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
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Do not take 2 doses at the same time or extra doses.
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If you are not sure what to do if you miss a dose, call your doctor.
How do I store and/or throw out this drug?
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Store in the original container at room temperature.
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Keep lid tightly closed.
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Store in a dry place. Do not store in a bathroom.
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Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
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Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
General drug facts
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If your symptoms or health problems do not get better or if they become worse, call your doctor.
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Do not share your drugs with others and do not take anyone else's drugs.
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Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
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If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Last Reviewed Date2022-04-26
Consumer Information Use and Disclaimer
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This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
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