Pleural biopsy

(A) Photomicrograph of pleural biopsy showing malignant mesothelioma.
(B) A positive stain is brown. The immunohistochemical panel supports the diagnosis of malignant mesothelioma with positive nuclear stain for Wilms tumor protein (WT-1).
(C) Positive nuclear and cytoplasmic stain for calretinin.
(D) Positive stain for D2-40.
(E) Negative stain for transcription termination factor-1 (TTF-1).
(F) Negative stain for MOC31.