Raltegravir: Patient drug information
What is this drug used for?
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No
It is used to treat HIV infection.
What do I need to tell my doctor BEFORE I take this drug?
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urn:lims:b498:s2705171
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No
If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
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urn:lims:b498:s2703781
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No
If you have liver disease.
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urn:lims:b498:s6519402
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No
If you are taking any of these drugs: Carbamazepine, etravirine, phenobarbital, phenytoin, rifampin, or tipranavir/ritonavir.
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urn:lims:b498:s6992939
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No
If you are taking an antacid.
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urn:lims:b498:s7432560
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Female
No
If you are pregnant, may become pregnant, or are breast-feeding. Before taking this drug, you will need to talk about the benefits and risks to you and the baby. You will also need to talk about the best way to prevent passing HIV to the baby.
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This is not a list of all drugs or health problems that interact with this drug.
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urn:lims:b498:s4194405
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Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take this drug?
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For all patients taking this drug:
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No
Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
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No
Have your blood work and other lab tests checked as you have been told by your doctor.
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urn:lims:b498:s4193926
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No
This drug is not a cure for HIV. Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well. Be sure to stay under the care of your doctor and have regular appointments.
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urn:lims:b498:s7432561
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No
This drug helps to lower how much HIV is in the blood. Lowering the amount of HIV in the blood until it is not detected on blood tests can help lower the risk of spreading HIV to others. There are also other ways to help prevent the spread of HIV to others. This includes using condoms during sex and not sharing needles and other injection equipment. Talk with your doctor or other health care provider about the best way to prevent spreading HIV to others.
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urn:lims:b498:s2697329
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No
If you have phenylketonuria (PKU), talk with your doctor. Some products have phenylalanine.
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urn:lims:b498:s4737803
No
Children:
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No
Not all products are meant for use in all children. Talk with the doctor before giving this drug to a child.
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No
If giving this drug to your child and your child's weight changes, talk with the doctor. The dose of this drug may need to be changed.
What are some side effects that I need to call my doctor about right away?
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WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
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urn:lims:b498:s2699066
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No
Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
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urn:lims:b498:s4192387
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No
Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
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No
Muscle or joint pain.
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urn:lims:b498:s2698255
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No
Muscle weakness.
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urn:lims:b498:s7210769
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No
Severe skin reactions may happen with this drug. These include Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and other serious reactions. Sometimes, body organs may also be affected. These reactions can be deadly. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin; red or irritated eyes; sores in your mouth, throat, nose, eyes, genitals, or any areas of skin; fever; chills; body aches; shortness of breath; or swollen glands.
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urn:lims:b498:s4194005
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No
Changes in your immune system can happen when you start taking drugs to treat HIV. If you have an infection that you did not know you had, it may show up when you take this drug. Tell your doctor right away if you have any new signs after you start this drug, even after taking it for several months. This includes signs of infection like fever, sore throat, weakness, cough, or shortness of breath.
What are some other side effects of this drug?
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urn:lims:b498:s4186184
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All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
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urn:lims:b498:s5014002
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No
Trouble sleeping.
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urn:lims:b498:s2698119
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No
Headache.
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urn:lims:b498:s6834228
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No
Feeling dizzy, tired, or weak.
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No
Upset stomach.
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urn:lims:b498:s2699671
No
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
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US
No
You may report side effects to your national health agency.
How is this drug best taken?
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urn:lims:b498:s2696083
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Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
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No
All products:
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No
Take with or without food.
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No
It is important that you do not miss or skip a dose of this drug during treatment.
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No
Do not run out of this drug.
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urn:lims:b498:s2697059
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No
If you are on dialysis, talk with your doctor.
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urn:lims:b498:s2705566
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Tablets:
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No
Swallow whole. Do not chew, break, or crush.
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urn:lims:b498:s2705349
No
Chewable tablets:
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urn:lims:b498:s4612552
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No
This drug may be chewed or swallowed whole.
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urn:lims:b498:s6992941
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No
If needed, the 25 mg tablets may be mixed with liquid like water, juice, or breast milk. Add tablets to a cup and add 5 mL of liquid for each tablet. The tablets will fall apart within 2 minutes. Crush any pieces left with a spoon before you take the dose. If any of the drug is left in the cup, add 5 mL of liquid, swirl, and drink.
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urn:lims:b498:s4680445
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No
After mixing, take your dose right away. Do not store for future use.
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urn:lims:b498:s4605512
No
Powder for suspension:
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urn:lims:b498:s5378084
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No
Do not open until you are ready to use.
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urn:lims:b498:s4992243
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No
Mix contents of the packet and 10 mL of water in the mixing cup. Gently swirl for 45 seconds; do not shake. Once mixed, measure the dose. This drug is to be taken within 30 minutes of mixing. Throw away any part not used after mixing.
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Measure liquid doses carefully. Use the measuring device that comes with this drug.
What do I do if I miss a dose?
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No
Take a missed dose as soon as you think about it.
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No
If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
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No
Do not take 2 doses at the same time or extra doses.
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No
If you are not sure what to do if you miss a dose, call your doctor.
How do I store and/or throw out this drug?
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urn:lims:b498:s2705324
No
All products:
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urn:lims:b498:s2699399
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No
Store in the original container at room temperature.
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urn:lims:b498:s2699266
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No
Store in a dry place. Do not store in a bathroom.
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urn:lims:b498:s2699678
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No
Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
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urn:lims:b498:s4194563
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No
Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
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urn:lims:b498:s4718514
No
Tablets and chewable tablets:
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urn:lims:b498:s7296615
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No
The bottle has a desiccant in it to keep the drug dry. Keep the desiccant in the bottle. Do not eat or swallow the desiccant.
General drug facts
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urn:lims:b498:s2699675
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No
If your symptoms or health problems do not get better or if they become worse, call your doctor.
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urn:lims:b498:s2699673
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No
Do not share your drugs with others and do not take anyone else's drugs.
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urn:lims:b498:s2699709
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US
No
Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
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urn:lims:b498:s2698721
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No
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Last Reviewed Date2024-03-01
Consumer Information Use and Disclaimer
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This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
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