Society guideline links: Gastrointestinal stromal tumors

Introduction — 

This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.

The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.

United States

●American College of Gastroenterology (ACG): Clinical guideline for the diagnosis and management of gastrointestinal subepithelial lesions (2023)

●American Gastroenterological Association (AGA): Clinical practice update on management of subepithelial lesions encountered during routine endoscopy – Expert review (2022)

Europe

●European Society of Gastrointestinal Endoscopy (ESGE): Guideline for endoscopic management of subepithelial lesions including neuroendocrine neoplasms (2022)

●European Society for Medical Oncology (ESMO)-European Reference Network for Rare Adult Solid Cancers (EURACAN)-European Reference Network for Genetic Tumour Risk Syndromes (GENTURIS): Clinical practice guideline for diagnosis, treatment and follow-up of gastrointestinal stromal tumours (2021)

United Kingdom

●British Sarcoma Group (BSG): Clinical practice guidelines on gastrointestinal stromal tumour (GIST) (2025)

●National Institute for Health and Care Excellence (NICE): Interventional procedures guidance on endoscopic full thickness removal of gastrointestinal stromal tumours of the stomach (2022)

●Royal College of Pathologists (RCPath): Standards and datasets for reporting cancers – Dataset for histopathological reporting of gastrointestinal stromal tumours (2020)

Japan

●[In English] Japan Society of Clinical Oncology (JSCO): Japanese clinical practice guidelines for gastrointestinal stromal tumor (GIST), 2022 (published 2024)

●[In Japanese] JSCO: GIST treatment guidelines, 4th edition (2022)