Drug class or substance | Mechanism |
Anticoagulants | Interfere with clot formation (secondary hemostasis) |
Antiplatelet agents, including NSAIDs | Interfere with platelet function (primary hemostasis) |
Glucocorticoids | Interfere with vascular integrity |
Antibiotics | Cause vitamin K deficiency, especially with longer use Some interfere with platelet function |
SSRIs | Interfere with platelet function (primary hemostasis) |
Alcohol | Complications of liver disease may affect clot formation and may cause thrombocytopenia May cause thrombocytopenia due to direct marrow toxicity |
Vitamin E | Interferes with vitamin K metabolism in some individuals |
Garlic | Interferes with platelet function in some individuals |
Gingko biloba | Unknown |
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