Version May 2024
| Feature | Copper IUD | Levonorgestrel 52 mg IUD | Ulipristal acetate 30 mg | Levonorgestrel 1.5 mg |
| Pregnancy risk | 0.1%[1] | 0.3%[4] | 1.2 to 1.8%[2,3] | 1.7 to 2.6%[2,3] |
| Timing of use relative to UPI | Typically, up to 5 days after UPI, but may be effective at any time in the menstrual cycle when urine pregnancy test is negative[1,5,6] | Current best evidence, up to 5 days after UPI, but may be effective at any time in the menstrual cycle when urine pregnancy test is negative[8] | Up to 5 days after UPI[7] | Up to 3 days after UPI, although may have efficacy up to 5 days[7] |
| Timing of use relative to predicted ovulation | Highly effective at any time in the cycle | Highly effective at any time in the cycle | Effective until the LH peak[9] | Effective until the LH surge begins[9] |
| Availability and access | Requires office visit and clinician insertion | Requires office visit and clinician insertion | Requires prescription | Available OTC |
| Cost | Covered by insurance, though high deductible can limit access; highest cost for uninsured | Covered by insurance, though high deductible can limit access; highest cost for uninsured | Covered by insurance:
| $40 to $50 OTC in pharmacies $10 to $25 online, though shipping necessitates advanced provision for some websites |
| Relationship to starting progestin-containing contraception | N/A, effective for contraception immediately | N/A, effective for contraception immediately | Wait 5 days to begin[10] | May start immediately[10] |
| BMI pregnancy risk | Highly effective regardless of BMI | Highly effective regardless of BMI | BMI 25 to 29.9 = 1.1% BMI ≥30 = 2.6%[11] | BMI 25 to 29.9 = 2.5% BMI ≥30 = 5.8%[11] |
| Works to prevent pregnancy if additional UPI in same cycle | Yes | Yes | No | No |
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