Eligibility criteria for GOG-249^[1]

For patients with tumors of endometrioid histology:

Cervical stromal invasion (stage II), regardless of other uterine risk factors

Age 70 years or older with one uterine risk factor

Age 50 years or older with two uterine risk factors

Or age 18 years or older with three uterine risk factors

Uterine risk factors included grade 2 or 3 tumor, outer-half depth of invasion, and lymphovascular invasion. Positive or negative peritoneal cytology was allowed.

For patients with serous or clear cell tumors:

Stage I to II disease, with negative peritoneal cytology

GOG: Gynecologic Oncology Group.

Reference:

Randall ME, Filiaci V, McMeekin DS, et al. Phase III trial: Adjuvant pelvic radiation therapy versus vaginal brachytherapy plus paclitaxel/carboplatin in high-intermediate and high-risk early-stage endometrial cancer. J Clin Oncol 2019; 37:JCO1801575. Epub ahead of print.

Graphic 121337 Version 1.0

خرید پکیج

Eligibility criteria for GOG-249[1]

Eligibility criteria for GOG-249^[1]