Normal wound healing follows an orderly progression involving initial hemostasis, inflammatory, proliferative, and remodeling phases. The chronic wound is frequently characterized by persistent inflammation, which damages the newly developing extracellular matrix.
Adapted from: Gomes A, Teixeira C, Ferraz R, et al. Wound-healing peptides for treatment of chronic diabetic foot ulcers and other infected skin injuries. Molecules 2017; 22:1743. Copyright © 2017 MDPI. Available at:
https://www.mdpi.com/1420-3049/22/10/1743 (Accessed on June 18, 2019). Reproduced under the terms of the
Creative Commons Attribution License.
Additional information from:
- Armstrong DG, Gurtner GC. A histologically hostile environment made more hospitable? Nat Rev Endocrinol 2018; 14:511.
