Baylor Texas Children's guideline for platelet transfusion for neonatal alloimmune thrombocytopenia (platelet count <100,000/microL)

IVIG: intravenous immunoglobulin.
* Major bleeding is defined as a recent episode (within 72 hours) of intracranial bleeding, pulmonary hemorrhage, frank rectal bleeding, and life-threatening bleeding requiring emergency fluid resuscitation or red blood cell transfusion.
¶ Ill-appearing includes infants with poor perfusion, lethargy, respiratory distress, and/or apnea. In other centers, the clinical status of the infant does not influence the platelet threshold trigger.
Δ IVIG is administered at a dose of 400 mg/kg per day for three to four days or 1 g/kg per day for 1 to 3 days following platelet transfusion.
◊ Platelet transfusion is provided if there is evidence of major bleeding, the platelet count falls below 30,000/microL, or the platelet count is below 50,000/microL with deterioration of the clinical status.