Neonates at increased risk for hypoglycemia

Neonates at increased risk for hypoglycemia (require glucose screening):

Symptoms of hypoglycemia

Large for gestational age (even without maternal diabetes)

Perinatal stress

Birth asphyxia/ischemia

Cesarean delivery for fetal distress

Maternal preeclampsia/eclampsia or hypertension

Intrauterine growth restriction or small for gestational age

Meconium aspiration syndrome, erythroblastosis fetalis, polycythemia, hypothermia

Premature or postmature delivery

Infant of diabetic mother

Family history of a genetic form of hypoglycemia

Congenital syndromes (eg, Beckwith-Wiedemann syndrome)

Abnormal physical features (eg, midline facial malformations, microphallus)

Neonates at risk for persistent hypoglycemia (require more extensive evaluation):

Severe hypoglycemia (eg, episode of symptomatic hypoglycemia)

Inability to consistently maintain preprandial plasma glucose >50 mg/dL up to 48 hours of life and >60 mg/dL after 48 hours of life

Family history of a genetic form of hypoglycemia

Congenital syndromes (eg, Beckwith-Wiedemann syndrome)

Original table modified for this publication. From: Thornton PS, Stanley CA, De Leon DD, et al. Recommendations from the Pediatric Endocrine Society for evaluation and management of persistent hypoglycemia in neonates, infants, and children. J Pediatr 2015; 167:238. Table used with the permission of Elsevier Inc. All rights reserved.

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Neonates at increased risk for hypoglycemia