AKT signaling in follicular thyroid carcinoma

PI3K: phosphoinositide 3-kinase; PIP2: phosphatidylinositol 4,5-bisphosphate; PIP3: phosphatidylinositol 3,4,5-trisphosphate; PDK1: 3-phosphoinositide-dependent protein kinase 1.

Adapted from: Xing M. Molecular pathogenesis and mechanisms of thyroid cancer. Nat Rev Cancer 2013; 13:184.

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