Biopsies from age- and sex-matched control (A) and affected (B) buttock skin were stained with hematoxylin and eosin. The arrow indicates the granular layer in the control. No granular layer is detectable in the biopsy from the affected individual. Magnification bar = 20 micron.
From: Fleckman P, Brumbaugh S. Absence of the granular layer and keratohyalin define a morphologically distinct subset of individuals with ichthyosis vulgaris. Exp Dermatol 2002; 11(4):327-36.
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