The illustrations depict worsening lymphedema in accordance with the International Society for Lymphology lymphedema staging
[1].
- Stage 0: Latent or subclinical lymphedema where swelling is not yet evident despite impaired lymph transport.
- Stage I: Mild lymphedema with accumulation of fluid which subsides with limb elevation. Pitting may occur.
- Stage II: Moderate lymphedema with swelling and pitting. Later in stage II, the limb may not pit as excess subcutaneous fat and fibrosis develop.
- Stage III: Severe lymphedema where pitting can be absent and trophic skin changes such as acanthosis, alterations in skin character and thickness, further deposition of fat and fibrosis, and warty overgrowths have developed.
