Esomeprazole: Patient drug information

What is this drug used for?

It is used to treat gastroesophageal reflux disease (GERD; acid reflux).
It is used to treat heartburn.
It is used to treat or prevent GI (gastrointestinal) ulcers caused by infection.
It is used to treat or prevent ulcers of the esophagus.
It is used to treat syndromes caused by lots of stomach acid.
It is used to treat or prevent nonsteroidal anti-inflammatory drugs (NSAID)-associated gastric ulcers in patients with a history of ulcers. Examples of NSAIDs include ibuprofen and naproxen.
It is used to lower the chance of bleeding ulcers after a certain procedure (endoscopy).
It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take this drug?

If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
If you are taking any of these drugs: Atazanavir, clopidogrel, nelfinavir, rifampin, rilpivirine, St. John's wort, or warfarin.
If you have any of these health problems: Black or bloody stools; heartburn with light-headedness, sweating, dizziness, or wheezing; chest pain; shoulder pain with shortness of breath; pain that spreads to the arms, neck, or shoulders; lightheadedness; sweating a lot; throwing up blood; or trouble or pain swallowing food.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
Do not take this drug for longer than you were told by your doctor.
This drug may affect certain lab tests. Tell all of your health care providers and lab workers that you take this drug.
This drug may raise the chance of hip, spine, and wrist fractures in people with weak bones (osteoporosis). The chance may be higher if you take this drug in high doses or for longer than a year, or if you are older than 50 years old.
Use care if you have risks for soft, brittle bones (osteoporosis). Some of these risks include drinking alcohol, smoking, taking steroids, taking drugs to treat seizures, or having family members with osteoporosis. Talk with your doctor about your risks of osteoporosis.
Rarely, low magnesium levels have happened in people taking drugs like this one for at least 3 months. Most of the time, this happened after 1 year of treatment. Low magnesium levels may lead to other electrolyte problems. You may need to have your blood work checked as your doctor has told you.
Rarely, long-term treatment (for instance longer than 3 years) with drugs like this one has caused low vitamin B-12 levels. Call your doctor right away if you have signs of low vitamin B-12 levels like shortness of breath, dizziness, abnormal heartbeat, muscle weakness, pale skin, tiredness, mood changes, or numbness or tingling in the arms or legs.
Lupus has happened with this drug, as well as lupus that has gotten worse in people who already have it. Tell your doctor if you have lupus. Call your doctor right away if you have signs of lupus like a rash on the cheeks or other body parts, change in skin color, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs.
The risk of stomach growths called fundic gland polyps may be higher in people who take this drug for more than 1 year. If you have questions, talk with the doctor.
Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
All products:
Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Signs of electrolyte problems like mood changes; confusion; muscle pain, cramps, or spasms; weakness; shakiness; change in balance; an abnormal heartbeat; seizures; loss of appetite; or severe upset stomach or throwing up.
Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
Very bad dizziness or passing out.
Bone pain.
A big weight loss.
This drug may raise the chance of a severe form of diarrhea called C diff-associated diarrhea (CDAD). Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat diarrhea without first checking with your doctor.
Severe skin reactions may happen with this drug. These include Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and other serious reactions. Sometimes, body organs may also be affected. These reactions can be deadly. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin; red or irritated eyes; sores in your mouth, throat, nose, eyes, genitals, or any areas of skin; fever; chills; body aches; shortness of breath; or swollen glands.
Injection:
Irritation where the shot is given.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
Headache.
Stomach pain or diarrhea.
Constipation.
Gas.
Dry mouth.
Upset stomach.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
Tablets:
Take at least 1 hour before meals with a full glass of water.
Swallow whole. Do not chew, break, or crush.
Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
Capsules:
Take at least 1 hour before meals with a full glass of water.
Swallow whole. Do not chew or crush.
Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
If you cannot swallow this drug whole, you may sprinkle the contents on applesauce. If you do this, swallow the mixture right away without chewing.
If mixing on applesauce, the applesauce should not be warm. Do not sprinkle on other liquids or foods.
After mixing, take your dose right away. Do not store for future use.
Those who have feeding tubes may make a liquid. Empty contents of capsule into a 60 mL syringe with 50 mL of water. Replace plunger and shake for 15 seconds. Flush feeding tube before and after this drug is taken.
Powder for suspension:
Take 1 hour before a meal.
Mix contents of 2.5 mg or 5 mg packets with 1 teaspoon (5 mL) of water, and the 10 mg, 20 mg, or 40 mg packets with 1 tablespoon (15 mL) of water. If 2 packets are needed, follow these steps with double the amount of water. Stir into the water then let sit for 2 to 3 minutes. Mix and drink.
Take your dose within 30 minutes after mixing. Throw away any part not used within 30 minutes of mixing.
Rinse cup with more water and drink.
Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
This drug may be given to those who have feeding tubes. For 2.5 mg or 5 mg packets, add 5 mL of water to a syringe then add the packet contents to the syringe. For 10 mg, 20 mg, or 40 mg packets, add 15 mL of water to a syringe then add the packet contents to the syringe. Replace plunger and shake. Let sit for 2 to 3 minutes. Shake again and give through the feeding tube. After giving this drug, refill syringe with same amount of water used, shake, and flush feeding tube.
Injection:
This drug is given as a shot into a vein or into a vein nonstop for a period of time.

What do I do if I miss a dose?

All oral products:
Take a missed dose as soon as you think about it.
If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
Do not take 2 doses at the same time or extra doses.
Injection:
Call your doctor to find out what to do.

How do I store and/or throw out this drug?

All oral products:
Store at room temperature in a dry place. Do not store in a bathroom.
Tablets and capsules:
Keep lid tightly closed.
Injection:
If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.
All products:
Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

General drug facts

If your symptoms or health problems do not get better or if they become worse, call your doctor.
Do not share your drugs with others and do not take anyone else's drugs.
Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

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Esomeprazole: Patient drug information