Version July 2025
5-HIAA: 5-hydroxyindoleacetic acid; CBC: complete blood count; CRP: C-reactive protein; CT: computed tomography; CXR: chest x-ray; FUO: fever of unknown origin; IGRA: interferon gamma release assay; LFTs: liver function tests; TB: tuberculosis; TSH: thyroid-stimulating hormone.
* Refer to UpToDate content on FUO.
¶ Refer to UpToDate content on evaluation of night sweats with localizing signs and/or symptoms.
Δ Refer to UpToDate content on acute phase reactants.
◊ Although there is no recommended time to wait between steps in evaluation of persistent sweating symptoms, two weeks is a reasonable period. If, at any point, localizing signs or symptoms develop, evaluate as indicated for suspected etiology. If sweating symptoms resolve, no further evaluation is necessary.
§ Refer to UpToDate content on management of pheochromocytoma.
¥ Refer to UpToDate content on management of carcinoid syndrome.