Version May 2024
Surgical aid (ophthalmic): Intravitreal: Inject 0.5 mL into a balanced salt solution-filled vitreous cavity.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Refer to adult dosing.
There are no adverse reactions listed in the manufacturer's labeling.
There are no contraindications listed in the manufacturer's labeling.
Other warnings/precautions:
• Administration: Ensure the syringe plunger moves smoothly prior to use; do not use if plunger does not move smoothly to prime the cannula.
• Appropriate use: Following sufficient staining, immediately remove all excess dye to prevent excessive staining.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution Prefilled Syringe, Intraocular:
TissueBlue: 0.025% (0.5 mL) [contains polyethylene glycol (macrogol)]
No
Solution Prefilled Syringe (TissueBlue Intraocular)
0.025% (per 0.5 mL): $181.68
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution Prefilled Syringe, Intraocular:
TissueBlue: 0.025% (0.5 mL)
Intravitreal: Attach a blunt cannula to the prefilled syringe and prime cannula (if syringe plunger does not move smoothly during priming, then discard). During administration, do not allow cannula to contact retina or allow dye to get under retina. Following sufficient staining (usually within a few seconds), immediately remove excess dye from vitreous cavity.
Surgical aid (ophthalmic): Used to selectively stain the internal limiting membrane.
None known.
There are no known significant interactions.
Absorption following intravitreal injection and removal of excess dye is negligible; fetal exposure is not expected.
It is not known if brilliant blue G is present in breast milk.
Absorption following intravitreal injection and removal of excess dye is negligible; exposure to an infant via breast milk is not expected.
Selectively stains the internal limiting membrane (not the epiretinal membrane or retina), thereby improving visualization of the membrane for removal.
Onset: Internal limiting membrane staining occurs within a few seconds.
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