Effect of remifentanil at different concentrations of propofol and sevoflurane

Effect of addition of remifentanil to probability of response to noxious stimulus, at different concentrations of propofol (A) and sevoflurane (B).

TOTS: tolerance to tetanic stimulation; vol%: end-tidal sevoflurane concentration

From: Kuizenga MH, Colin PJ, Reyntjens KM, et al. Population Pharmacodynamics of Propofol and Sevoflurane in Healthy Volunteers Using a Clinical Score and the Patient State Index: A Crossover Study. Anesthesiology 2019; 131:1223. DOI: 10.1097/ALN.0000000000002966. Copyright © 2019 the American Society of Anesthesiologists. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.

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Effect of remifentanil at different concentrations of propofol and sevoflurane