Amputation risk based on Wound-Ischemia-foot Infection system

Wound grade (0-3)	Ischemia grade (0-3)	foot Infection grade (0-3)
Wound grade (0-3)	Ischemia grade (0-3)	0	1	2	3
0	0	VL	VL	L	M
1	0	VL	VL	M	M
0	1	VL	L	M	H
1	1	VL	L	M	H
0	2	L	L	M	H
1	2	L	M	H	H
0	3	L	M	M	H
1	3	M	M	H	H
2	0	L	L	M	H
3	0	M	M	H	H
2	1	M	M	H	H
3	1	M	M	H	H
2	2	M	M	H	H
3	2	H	H	H	H
2	3	H	H	H	H
3	3	H	H	H	H

The table shows the effect of worsening Wound, Ischemia, and foot Infection (WIfI) clinical stage and the prognosis of chronic limb-threatening ischemia. The clinical stages 1, 2, 3, and 4 correspond to the VL, L, M, and H amputation risk categories. As an example, a foot with WIfI grades 002 is clinical stage 1 and has a low risk for amputation at one year, whereas a foot with WIfI grades 223 is clinical stage 4 and is high risk.

VL: very low risk; L: low risk; M: moderate risk; H: high risk.

Adapted from: Mills JL, Conte MS, Armstrong DG, et al. The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: Risk stratification based on Wound, Ischemia, and foot Infection. J Vasc Surg 2014; 59:220.

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Amputation risk based on Wound-Ischemia-foot Infection system