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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Recommended post-exposure vaccination schedules for anthrax vaccine absorbed[1]

Recommended post-exposure vaccination schedules for anthrax vaccine absorbed[1]
  Dose (mL) Route of administration Schedule
Standard regimen 0.5 Subcutaneous 3 doses post exposure:
  • 0 weeks
  • 2 weeks
  • 4 weeks
Dose-sparing regimens* 0.5 Subcutaneous or intramuscular 2 doses post exposure:
  • 0 weeks
  • 2 to 4 weeks
0.25 3 doses post exposure:
  • 0 weeks
  • 2 weeks
  • 4 weeks

For post-exposure prophylaxis, vaccines are administered in combination with antimicrobial prophylaxis regimens. These vaccine regimens are for individuals who did not receive pre-exposure vaccination. Refer to other UpToDate content for details on post-exposure prophylaxis in individuals who have already received anthrax vaccination.

If supplies of anthrax vaccine adsorbed (AVA) are limited, another option for post-exposure prophylaxis is anthrax vaccine adsorbed, adjuvanted (AVA-adjuvanted). It is administered as two intramuscular doses of 0.5 mL each, given at 0 and 2 weeks following exposure.

* A dose-sparing regimen of anthrax vaccine adsorbed can be used if the supply is not sufficient to allow standard vaccination for all exposed individuals.

¶ Vaccine can be administered intramuscularly if subcutaneous administration poses significant challenges that might delay or preclude vaccination.
Reference:
  1. Bower WA, Schiffer J, Atmar RL, et al. Use of Anthrax Vaccine in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2019. MMWR Recomm Rep 2019; 68:1.
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