An approach to diagnosis of prosthetic valve endocarditis

Issues related to clinical manifestations, diagnosis, and treatment of PVE are discussed further in the text (refer to UpToDate topics on clinical manifestations, diagnosis, and treatment of PVE).

18F-FDG PET/CT: 18F-fluorodeoxyglucose positron emission computed tomography; EKG CTA: electrocardiogram-gated cardiac computed angiography; PVE: prosthetic valve endocarditis; TAVI: transcatheter aortic valve implantation; TEE: transesophageal echocardiogram; TTE: transthoracic echocardiogram.

* Refer to 2023 Duke-ISCVID criteria for organisms that typically cause endocarditis.

¶ The choice of cardiac imaging may be impacted by local availability and expertise. If advanced imaging is not readily available, options include transfer or making a clinical determination regarding completing a course of empiric treatment for PVE in the absence of definitive diagnostic imaging.

Δ Correlate cardiac imaging with microbiologic and clinical criteria to establish diagnosis of PVE.

◊ Make clinical determination regarding completing course of empiric treatment for PVE in the absence of definitive diagnostic imaging.

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An approach to diagnosis of prosthetic valve endocarditis