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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Clinical manifestations of COVID-19-associated multisystem inflammatory syndrome in children and adolescents

Clinical manifestations of COVID-19-associated multisystem inflammatory syndrome in children and adolescents
  Frequency* (%)
Presenting symptoms
  • Persistent fevers (median duration 4 to 6 days)
100
  • Gastrointestinal symptoms (abdominal pain, vomiting, diarrhea)
60 to 100
  • Rash
45 to 76
  • Conjunctivitis
30 to 81
  • Mucous membrane involvement
27 to 76
  • Neurocognitive symptoms (headache, lethargy, confusion)
29 to 58
  • Respiratory symptoms (tachypnea, labored breathing)
21 to 65
  • Sore throat
10 to 16
  • Myalgias
8 to 17
  • Swollen hands/feet
9 to 16
  • Lymphadenopathy
6 to 16
Clinical findings
  • Shock
32 to 76
  • Criteria for complete Kawasaki disease met
22 to 64
  • Myocardial dysfunction (by echocardiogram or elevated troponin/BNP)
51 to 90
  • Arrhythmia
12
  • Acute respiratory failure requiring noninvasive or invasive ventilation
28 to 52
  • Acute kidney injury
8 to 52
  • Serositis (small pleural, pericardial, and ascitic effusions)
24 to 57
  • Hepatitis or hepatomegaly
5 to 21
  • Encephalopathy, seizures, coma, or meningoencephalitis
6 to 7
Laboratory findings
  • Abnormal blood cell counts
  • Lymphocytopenia
80 to 95
  • Neutrophilia
68 to 90
  • Mild anemia
70
  • Thrombocytopenia
31 to 80
  • Elevated inflammatory markers
  • C-reactive protein
90 to 100
  • Erythrocyte sedimentation rate
75 to 80
  • D-dimer
67 to 100
  • Fibrinogen
80 to 100
  • Ferritin
55 to 76
  • Procalcitonin
80 to 95
  • Interleukin 6
80 to 100
  • Elevated cardiac markers
  • Troponin
50 to 90
  • BNP or NT-pro-BNP
73 to 90
  • Hypoalbuminemia
48 to 95
  • Mildly elevated liver enzymes
62 to 70
  • Elevated lactate dehydrogenase
10 to 60
  • Hypertriglyceridemia
70
Imaging findings
  • Echocardiogram
  • Depressed LV function
31 to 58
  • Coronary artery dilation/aneurysm
8 to 38
  • Other findings can include mitral regurgitation and pericardial effusion
--
  • Chest radiograph
  • Normal in many patients
--
  • Abnormal findings included small pleural effusions, patchy consolidations, focal consolidation, and atelectasis
--
  • Chest CT
  • Findings generally similar to those on chest radiograph
--
  • A few patients had nodular ground-glass opacification
--
  • Abdominal imaging (ultrasound and/or CT)
  • Findings are nonspecific, including free fluid, ascites, bowel and mesenteric inflammation, including terminal ileitis, mesenteric adenopathy/adenitis, and pericholecystic edema
--
COVID-19: coronavirus disease 2019; BNP: brain natriuretic peptide; NT-pro-BNP: N-terminal pro-BNP; LV: left ventricular; CT: computed tomography.
* The frequencies listed in this table represent the proportion of patients with each finding among those tested or assessed for the finding. Not all patients were tested or assessed for each.
Graphic 128294 Version 8.0

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