Introduction —
This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.
The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.
International
●International recommendations on postoperative management for potentially resectable locally recurrent nasopharyngeal carcinoma (2024)
●International Society of Oral Oncology (ISOO)-Multinational Association for Supportive Care in Cancer (MASCC)-American Society of Clinical Oncology (ASCO): Guideline for the prevention and management of osteoradionecrosis in patients with head and neck cancer treated with radiation therapy (2024)
●Society for Immunotherapy of Cancer (SITC): Head and neck squamous cell carcinoma immunotherapy guideline (updated 2024)
●International recommendations on reirradiation by intensity modulated radiation therapy for locally recurrent nasopharyngeal carcinoma (2021)
●International guideline on dose prioritization and acceptance criteria in radiation therapy planning for nasopharyngeal carcinoma (2019)
●Enhanced Recovery After Surgery Society (ERAS Society): Consensus review and recommendations on optimal perioperative care in major head and neck cancer surgery with free flap reconstruction (2017)
Canada
●Cancer Care Ontario (CCO): Guideline on the role of endolaryngeal surgery (with or without laser) versus radiotherapy in the management of early (T1) glottic cancer (2023)
●CCO: Guideline on systemic therapy in the curative treatment of head and neck squamous cell cancer (2022)
●CCO: Guideline on routine human papilloma virus (HPV) testing in squamous cell head and neck cancer (2020)
United States
●American Society of Clinical Oncology (ASCO): Guideline on transoral robotic surgery in the multidisciplinary care of patients with oropharyngeal squamous cell carcinoma (2025)
●College of American Pathologists (CAP): Guideline on human papillomavirus testing in head and neck carcinomas, update (2025)
●American Society for Radiation Oncology (ASTRO): Clinical practice guideline on radiation therapy for HPV-positive oropharyngeal squamous cell carcinoma (2024)
●International Society of Oral Oncology (ISOO)-Multinational Association for Supportive Care in Cancer (MASCC)-ASCO: Guideline for the prevention and management of osteoradionecrosis in patients with head and neck cancer treated with radiation therapy (2024)
●American College of Radiology (ACR): ACR Appropriateness Criteria on staging and post-therapy assessment of head and neck cancer (2023)
●Expert consensus statement – Management of dysphagia in head and neck cancer patients (2023)
●ASCO: Guideline on immunotherapy and biomarker testing in recurrent and metastatic head and neck cancers (2022)
●ASCO: Guideline for the management of salivary gland malignancy (2021)
●Chinese Society of Clinical Oncology (CSCO) and ASCO: Guideline on chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma (2021)
●ASCO: Guideline for the diagnosis and management of squamous cell carcinoma of unknown primary in the head and neck (2020)
●ASCO: Clinical practice guideline for the management of the neck in squamous cell carcinoma of the oral cavity and oropharynx (2019)
●ASCO: Clinical practice guideline endorsement of the College of American Pathologists (CAP) guideline on human papillomavirus testing in head and neck carcinomas (2018)
●ASCO: Clinical practice guideline endorsement of the American Cancer Society (ACS) guideline on head and neck cancer survivorship care (2017)
●ASCO: Clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer, update (2017)
●ASCO: Endorsement of the American Society for Radiation Oncology (ASTRO) evidence-based clinical practice guideline on radiation therapy for oropharyngeal squamous cell carcinoma (2017)
Europe
●European Society for Medical Oncology (ESMO)–European Reference Network for Rare Adult Solid Tumours (EURACAN): Clinical practice guideline for diagnosis, treatment and follow-up of sinonasal malignancy (2025)
●European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT): Recommendations for diagnosis and management of olfactory neuroblastoma in children and adolescents (2024)
●ESMO–EURACAN: Clinical practice guideline for nasopharyngeal carcinoma – Adjuvant therapy and first-line treatment for recurrent/metastatic disease, update (2023)
•ESMO-EURACAN: Nasopharyngeal carcinoma – Clinical practice guidelines for diagnosis, treatment and follow-up of nasopharyngeal carcinoma (2020)
●European Head and Neck Society (EHNS): Recommendations for head and neck cancer survivorship care (2022)
●ESMO–EURACAN: Clinical practice guideline for diagnosis, treatment and follow-up of salivary gland cancer (2022)
●EXPeRT/Paediatric Rare Tumours Network - European Registry (PARTNER): Diagnosis and treatment recommendations for salivary gland carcinoma in children and adolescents (2021)
●EXPeRT/PARTNER: Diagnostic and therapeutic recommendations for nasopharyngeal carcinoma in children and adolescents (2021)
●EHNS-ESMO-European SocieTy for Radiotherapy and Oncology (ESTRO): Clinical practice guidelines for diagnosis, treatment and follow-up of squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx (2020)
United Kingdom
●Head and neck cancer – United Kingdom national multidisciplinary guidelines, sixth edition (2024)
●National Institute for Health and Care Excellence (NICE): Quality standard on head and neck cancer (2017)
India
●Indian clinical practice consensus guidelines for the management of hypopharyngeal cancer, 2022 update (published 2024)
●Indian clinical practice consensus guidelines for the management of laryngeal cancer, 2022 update (published 2024)
●Indian clinical practice consensus guidelines for the management of locoregional hypopharyngeal cancer, 2023 update (published 2024)
●Indian clinical practice consensus guidelines for the management of nasopharyngeal cancer, 2023 update (published 2024)
●Indian clinical practice consensus guidelines for the management of oral cavity cancer, 2023 update (published 2024)
●Indian clinical practice consensus guidelines for the management of oropharyngeal cancer, 2022 update (published 2024)
●Indian clinical practice consensus guidelines for the management of recurrent, persistent, or metastatic squamous cell carcinoma of head-and-neck, 2023 update (published 2024)
●Pan-Asian adaptation of the European Head and Neck Society (EHNS)–European Society for Medical Oncology (ESMO)–European SocieTy for Radiotherapy and Oncology (ESTRO) clinical practice guidelines for the diagnosis, treatment, and follow-up of patients with squamous cell carcinoma of the head and neck (2021)
●Indian Council of Medical Research (ICMR): Consensus document for management of larynx and hypopharynx cancers (2017)
Australia–New Zealand
●Clinical Oncology Society of Australia (COSA): Evidence-based practice guidelines for the nutritional management of adult patients with head and neck cancer
Japan
●[In English] Japanese Society of Oral Oncology (JSOO) and Japanese Society of Oral and Maxillofacial Surgeons (JSOMS): Japanese clinical practice guidelines for oral cancer, 2023 (published 2025)
●[In English] Japan Society for Head and Neck Cancer (JSHNC): Summary of Japanese clinical practice guidelines for head and neck cancer, 2022 update (published 2024)
●[In Japanese] JSOO and JSOMS: Oral cancer treatment guidelines, 4th edition (2023)
●[In English] Pan-Asian adaptation of the European Head and Neck Society (EHNS)–European Society for Medical Oncology (ESMO)–European SocieTy for Radiotherapy and Oncology (ESTRO) clinical practice guidelines for the diagnosis, treatment, and follow-up of patients with squamous cell carcinoma of the head and neck (2021)
●[In Japanese] Japanese Society of Medical Oncology (JSMO): Head and neck cancer chemotherapy guide, 2nd edition (2018)
