Coronary artery aneurysm associations in Kawasaki disease

Univariate associations in DC with CAAs (n = 117, 13.0%)
Characteristic	Odds ratio (95% CI)
Age at fever onset <6 months	3.71 (2.06-6.68)
Asian race reported	2.29 (1.51-3.47)
Days of fever (>1 day)	1.11 (0.99-1.23)
Maximum Z-score at baseline >1.00	2.35 (1.97-2.79)
Maximum Z-score at baseline ≥2.00	9.01 (5.81-14.0)
White blood cell count ≥16 cells/mm³	2.43 (1.64-3.61)
Hemoglobin <10.3 g/dL	1.98 (1.28-3.05)
Hematocrit <32	2.19 (1.47-3.27)
CRP ≥13 mg/dL	2.13 (1.41-3.21)
Albumin <3.2 g/dL	3.63 (2.23-5.92)
Final multivariable model: c statistic = 0.82 (Hosmer-Lemeshow, p = 0.816)
Maximum Z-score at baseline ≥2.00	9.82 (6.09-15.9)
Age at fever onset <6 months	3.02 (1.5-6.06)
Any Asian race reported	1.95 (1.2-3.17)
CRP ≥13 mg/dL	2.06 (1.3-3.26)

DC: development cohort; CAA: coronary artery aneurysm; CRP: C-reactive protein.

From: Son MBF, Gauvreau K, Tremoulet AH, et al. Risk model development and validation for prediction of coronary artery aneurysms in Kawasaki disease in a North American population. J Am Heart Assoc 2019; 8:e011319. https://www.ahajournals.org/doi/10.1161/JAHA.118.011319. Copyright © 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. Modified with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/).

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Coronary artery aneurysm associations in Kawasaki disease