Version July 2025
There are no adverse reactions listed in the manufacturer's labeling.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution for Perfusion:
Custodiol HTK: (500 mL, 1000 mL, 2000 mL, 5000 mL)
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution for Perfusion:
Custodiol HTK: (1000 mL, 2000 mL, 5000 mL)
Solution is not for continuous perfusion; leave solution in the organ vasculature during hypothermic storage and transportation. Perfuse with a maximum hydrostatic pressure of 120 mm Hg. Not for IV or intra-arterial administration.
Solution is not for continuous perfusion; leave solution in the organ vasculature during hypothermic storage and transportation. Perfuse with a maximum hydrostatic pressure of 120 mm Hg. Not for IV or intra-arterial administration.
Donor organ perfusion: Flushing and perfusion of donor heart, kidneys, liver, and pancreas prior to or immediately after removal from the donor.
The Institute for Safe Medication Practices (ISMP) includes this medication among its list of drug classes (cardioplegic solution) which have a heightened risk of causing significant patient harm when used in error (High-Alert Medications in Acute Care Settings).
Custodiol [US, Canada, and multiple international markets] is also the brand name for bisacodyl [Indonesia].
None known.
Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the drug interactions program
There are no known significant interactions.
