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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Operative, oncologic, and pregnancy outcomes of women undergoing radical trachelectomy

Operative, oncologic, and pregnancy outcomes of women undergoing radical trachelectomy
Outcome Radical trachelectomy route Total
Vaginal Abdominal Laparoscopic
Number of patients 1491 955 120 2566
Operative time (minute) 180 (120-330) 240 (132-436) 272 (231-360) 226 (120-479)
Estimated blood loss (mL) 254 (100-486) 322 (280-2510) 63 (23-692) 300 (23-2510)
Intraoperative conversion to hysterectomy 26 (3.9) 111 (12.6) 14 (11.8) 151 (9)
Receipt of postoperative RT 47 (4.4) 42 (5.4) 0 (0) 89 (4.7)
Follow-up (month) 50.9 (9.8-202) 38 (2-66) 25 (3.5-52.8) 48 (2-202)
Recurrence rate (%) 3.8 (0-9.9) 3.3 (0-9.8) 0 (0-25)* 3.3 (0-25)*
Time to recurrence (month) 26.1 (11-44) 26 (12.5-26) 8 26 (8-44)
5-year recurrence-free survival (%) 94.4 (88-97.3) 96.3 NR 94.6 (88-97.3)
Death rate from disease (%) 1.7 (0-3) 1.5 (0-1.7) 0 (0-3.7) 1.6 (0-3.7)
5-year overall survival (%) 97.4 (95-99) 98.6 NR 97.4 (95-99)
Posttrachelectomy pregnancies 177 41 7 225
  • Pregnancy rate
37.8 10.4 9.2 23.9
  • Nonviable delivery or abortion
43 (24.3) 10 (24.4) 3 (42.9) 56 (24.9)
  • Preterm delivery
60 (33.9) 16 (39) 4 (57.1) 80 (35.6)
  • Term delivery
74 (41.8) 15 (36.6) 0 (0) 89 (39.6)
  • Live birth rateΔ
75.7 75.6 57.1 75.1
Data are n, median (range), or n (%).
RT: radiation therapy; NR: not reported in any article within the subgroup.
* The 25% rate was an outlying value from an article reporting only 4 patients who underwent radical trachelectomy.[1]
¶ Reported from only one article in the cohort.
Δ Live births represent term and preterm deliveries.
From: Smith ES, Moon AS, O'Hanlon R, et al. Radical trachelectomy for the treatment of early-stage cervical cancer: A systematic review. Obstet Gynecol 2020; 136:533. DOI: 10.1097/AOG.0000000000003952. Copyright © 2020 American College of Obstetricians and Gynecologists. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.
Reference:
  1. Hong DG, Lee YS, Park NY, et al. Robotic uterine artery preservation and nerve-sparing radical trachelectomy with bilateral pelvic lymphadenectomy in earlystage cervical cancer. Int J Gynecol Cancer 2011; 21:391.
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