Overview of the symptomatic treatment of dystonia in adults

The treatment of dystonia is symptomatic. Management options include oral medications, botulinum toxin (BoNT) injections, and deep brain stimulation (DBS). The choice among therapies depends on the age of the patient, the type of dystonia (eg, focal versus generalized), symptom severity, and patient preference. Patients with refractory dystonia should be referred to movement disorder specialty clinics for discussion of potential surgical options.

VMAT2: vesicular monoamine transporter type 2.
* In adults with newly diagnosed dystonia, a levodopa trial is appropriate in those with a family history of dopa-responsive dystonia or parkinsonism, and in those for whom the onset of dystonia may have been in childhood or adolescence.
¶ Partial responders may continue prior therapy if the benefit is felt to be sufficient.

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Overview of the symptomatic treatment of dystonia in adults